Priscilla is the tale of two drag-queens (Anthony/Mitzi and Adam/Felicia) and a transsexual (Bernadette) contracted to perform a drag show at a resort in Alice Springs, in the remote Australian desert. They embark on their lengthy road trip from Sydney aboard Priscilla, their lavender bus. En route, it is revealed that the woman they’ve contracted with is Anthony’s wife. When their bus breaks down in the middle of nowhere, it is repaired by drag fan Bob, who accompanies them on the rest of the trip.